| Proteinuria level predicts renal outcome in lupus nephritis - Medical Xpress |
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(HealthDay)—Proteinuria levels at 12 months are the best predictor of long-term renal outcome in patients with lupus nephritis, according to a study published in the May issue of Arthritis & Rheumatology. Maria Dall'Era, M.D., from the University of California in San Francisco, and colleagues analyzed data from the Euro-Lupus Nephritis Trial to evaluate the performance of proteinuria, serum creatinine (Cr), and urinary red blood cells (RBCs) as predictors of good long-term renal outcome (defined as a serum Cr value ?1.0 mg/dL) in patients with lupus nephritis. Seventy-six patients were followed for a minimum of seven years. The researchers found that a proteinuria value of The authors suggest "that urinary RBCs should not be included as a component of clinical trial response criteria in lupus nephritis." One author disclosed financial ties to the pharmaceutical industry. Explore further: Lower mortality rates among Asian and Hispanic lupus patients More information: Abstract
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