Dialysis world news


(+)-naloxone blocks opioid addiction by an immunologic mechanism.
EurekAlert: IMAGE: This is concept art depicting addiction by Joshua Burton (School of Medical Sciences, University of Adelaide). Click here for more information. "The drug (+)-naloxone automatically shuts down the addiction. It shuts down the need to take opioids, it cuts out behaviours associated with addiction, and the neurochemistry in the brain changes – dopamine, which is the chemical important for providing that sense of 'reward' from the drug, is no longer produced."

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Obatoclax and flavopiridol for multiple myeloma.
EurekAlert: The study published online in the journal Cancer Research details a dramatic increase in multiple myeloma cell death caused by a combination of the drugs obatoclax and flavopiridol. The researchers, led by Steven Grant, M.D., Shirley Carter Olsson and Sture Gordon Olsson Chair in Oncology Research, associate director for translational research, program co-leader and member of Developmental Therapeutics and member of the Cancer Cell Signaling program at VCU Massey Cancer Center, found that the two drugs worked together through different mechanisms to promote a form of cell suicide known as apoptosis.

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Meditation reduces activity of inflammation-associated genes.
EurekAlert: What to do? Researchers at UCLA now report that a simple meditation program lasting just eight weeks reduced loneliness in older adults. Further, knowing that loneliness is associated with an increase in the activity of inflammation-related genes that can promote a variety of diseases, the researchers examined gene expression and found that this same form of meditation significantly reduced expression of inflammatory genes.

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Glial lymphatic system identified in the brain.
URMC: A previously unrecognized system that drains waste from the brain at a rapid clip has been discovered by neuroscientists at the University of Rochester Medical Center. The findings were published online August 15 in Science Translational Medicine.

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Toxoplasma gondi infection linked to suicide attempts; T. gondi risk higher in dialysis patients
MSU: A parasite thought to be harmless and found in many people may actually be causing subtle changes in the brain, leading to suicide attempts. New research appearing in the August issue of The Journal of Clinical Psychiatry adds to the growing work linking an infection caused by the Toxoplasma gondii parasite to suicide attempts. Michigan State University’s Lena Brundin was one of the lead researchers on the team.

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